The short answer
Possibly. Amla extract slows platelet clumping, which is also how aspirin and clopidogrel prevent clots. In a small study in Hyderabad, 10 people with type 2 diabetes took amla extract, aspirin, clopidogrel, or amla with one of the drugs. Every treatment, amla alone included, reduced platelet clumping and lengthened bleeding time.
The study did not show how much amla added to either drug, or whether anyone bled more. Nobody has tested amla with warfarin or acenocoumarol, which work on clotting in a different way. If you take any blood thinner, tell your prescribing doctor before you start amla capsules or extract, and ask whether anything should be checked.
Aspirin is sold in India as Ecosprin, warfarin as Warf, and acenocoumarol, a drug of the same family as warfarin, as Acitrom.
At a glance
| What was seen | How it may work | Direction | Evidence |
|---|---|---|---|
| Less platelet clumping and longer bleeding time with amla, alone and with aspirin or clopidogrel[1][3] | Platelet inhibition | May add to the anti-platelet effect; no clinical bleeding rate in the available summary | Small clinical study |
| Less platelet clumping after 12 weeks of amla extract[2] | Platelet inhibition | Same direction as aspirin and clopidogrel | Small clinical study |
No listing is not a clearance. A missing interaction here never means a combination is safe.
The evidence, study by study
Crossover study in type 2 diabetes, Hyderabad, 2014 Small clinical study
At Nizam's Institute of Medical Sciences, 10 people with type 2 diabetes took each treatment in turn. These were amla extract (500 mg), aspirin as Ecosprin (75 mg), clopidogrel (75 mg), and amla with each drug. Each was given as a single dose and then daily for 10 days. All treatments, amla alone included, reduced platelet aggregation and lengthened bleeding and clotting times compared with baseline. The study was open-label, and its abstract gives no head-to-head numbers between amla with a drug and the drug alone.[1]
Single-group study in overweight adults, United States, 2015 Small clinical study
Overweight adults in Ohio took a standardised amla extract (CAPROS, 500 mg twice a day) for 12 weeks. Platelet clumping in response to two standard triggers, ADP and collagen, fell compared with their two baseline visits. There was no placebo group, and people taking aspirin or several heart medicines were excluded, so it shows amla's own effect, not an interaction.[2]
What your doctor may watch for
- Unusual bruising or bleeding, such as bleeding gums, nosebleeds or black stools.
- INR, if you take warfarin. Its label says INR should be checked more often when a herbal product is started or stopped. INR does not measure the effect of aspirin or clopidogrel.[4]
What to tell your prescribing doctor
You can read this out, or show them this page:
“I am taking, or planning to take, amla (fruit, juice, powder or capsules, and how much) along with my blood thinner. A small study found amla extract reduces platelet clumping, including when taken with aspirin or clopidogrel. Is there anything you would like to check, and what bleeding signs should I watch for?”
Withheld until review
Questions people ask
Related
Amla and blood pressure medicines
Two trials disagree. One found amla lowered blood pressure further in people on BP medicines; a larger one found no extra effect.
InteractionArjuna and blood thinners
In the lab, arjuna bark extract slowed platelet clumping and blocked enzymes that clear warfarin. We found no study of bleeding or INR with blood thinners.
InteractionTurmeric and blood thinners
Two reports describe a raised INR after turmeric in people on warfarin-type blood thinners. Blood thinners leave little margin.
InteractionGinger (adrak) and warfarin
Two women on blood thinners had a high INR after ginger supplements, and ginger users on warfarin reported more bleeding. One small study found no change.
Sources
- Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21:579-585. PMID 24291054.
- Khanna S, Das A, Spieldenner J, Rink C, Roy S. Supplementation of a standardized extract from Phyllanthus emblica improves cardiovascular risk factors and platelet aggregation in overweight/class-1 obese adults. J Med Food. 2015;18:415-420. PMID 25756303.
- Memorial Sloan Kettering Cancer Center. About Herbs: Emblica officinalis.
- Warfarin sodium tablets, US prescribing information (DailyMed).
Updated 4 November 2026
Taking amla with other medicines? A vaidya can check your full list.
Medicine Check · ₹299