Herb and medicine interaction

Shatavari and diuretics (water tablets)

Shatavari (Asparagus racemosus) with diuretics (water tablets).

Theoretical riskPending medical review

The short answer

Not known in people. We found no study of shatavari taken with a diuretic (water tablet). In one rat study from Manipal, a water extract of shatavari root increased urine output, but only at the highest of the three doses tested. Furosemide (Lasix) was used as a comparison in that study, and was never given with shatavari.

If shatavari had the same effect in people, it could add to the fluid and salt loss a water tablet causes. Nobody has measured this. If you take a diuretic, tell your prescribing doctor before you start shatavari, and ask whether your blood pressure, salts (electrolytes) and kidney function should be checked.

Diuretics sold in India include Lasix (furosemide), Dytor (torsemide), Aquazide (hydrochlorothiazide) and Aldactone (spironolactone).

At a glance

What was seenHow it may workDirectionEvidence
More urine output in rats, at the highest dose only[1]Diuretic effect of the root extractCould add to fluid and salt loss from a diuretic; untestedAnimal

No listing is not a clearance. A missing interaction here never means a combination is safe.

The evidence, study by study

Rat study, Manipal, 2010 Animal

Rats were given a water extract of shatavari root at 800, 1600 or 3200 mg per kg of body weight, or furosemide, or salt water. Only the 3200 mg per kg dose increased urine output significantly. The abstract gives neither urine volumes nor the number of rats. A dose that high in rats says little about the churna or tablets people take.[1]

What your doctor may watch for

  • Blood pressure, and any dizziness or faintness after you start shatavari.
  • Sodium, potassium and kidney function. The furosemide label says too much of the drug can cause water and electrolyte depletion and calls for careful medical supervision.[2]

What to tell your prescribing doctor

You can read this out, or show them this page:

“I am taking, or planning to take, shatavari (name of product, dose) along with my water tablet. A rat study found shatavari root increased urine output. Should my blood pressure, electrolytes or kidney function be checked?”

Withheld until review

Dose adjustments and any “no known interaction” clearance appear only after a vaidya on our medical board has reviewed this page. Why we hold these back

Questions people ask

Is shatavari a diuretic?

The Manipal authors note that Ayurveda has used it as one. In their rat test it increased urine output only at a very high dose. Whether it does so in people is not known.[1]

Does the type of shatavari product matter?

The rat study used a water extract of the root. Churna, granules, tablets and multi-herb mixes are made differently, and none has been tested with a diuretic. Take the pack itself to your appointment so your doctor can see the ingredients.[1]

Related

Sources

  1. Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59:3-6. PMID 20931905.
  2. Furosemide injection, US prescribing information, boxed warning (DailyMed).

Awaiting review by The Good Vaidya Medical Board. Prepared from the sources below and checked against each one.

Published 4 November 2026 · Last updated 4 November 2026

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