The short answer
Not known. We found no interaction study, one that measures drug levels, of turmeric with omeprazole, pantoprazole or antacids. One 2023 trial gave curcumin capsules, omeprazole or both to 206 people with indigestion for four weeks. It was testing symptom relief, not an interaction, and it did not measure drug levels.
That trial was later corrected, and we could not read the correction in full. All of this concerns curcumin capsules. Haldi in food is a different exposure and has not been tested either. If you take an acidity medicine regularly and want to add turmeric or curcumin capsules, tell your prescribing doctor, especially if your stomach symptoms continue or get worse.
Pantoprazole is sold in India as Pan 40, omeprazole as Omez, and pantoprazole with domperidone as Pan-D. Antacid gels include Digene.
At a glance
| What was seen | How it may work | Direction | Evidence |
|---|---|---|---|
| Curcumin given with omeprazole in a trial of indigestion symptoms[1][2] | Not studied; drug levels were not measured | Not known | RCT |
No listing is not a clearance. A missing interaction here never means a combination is safe.
The evidence, study by study
Randomised trial in functional dyspepsia, 2023 RCT
In this trial, 206 people with functional dyspepsia, indigestion with no cause found on tests, took curcumin (500 mg four times a day), omeprazole (20 mg a day) or both for 28 days, and 151 finished. It compared symptom relief and did not look for an interaction. A correction was published in 2024. Its opening says recruitment began in 2019 but the trial was registered only in 2022. We could not open the rest, so we do not report the trial's detailed results here.[1]
What your doctor may watch for
- Stomach symptoms that continue or get worse, whatever you are taking for them.
What to tell your prescribing doctor
You can read this out, or show them this page:
“I am taking, or planning to take, turmeric or curcumin (name of product, how much) along with my acidity medicine (name). A symptom trial gave curcumin with omeprazole, but it did not measure drug levels. Is there anything you would want to check?”
Withheld until review
Questions people ask
Does turmeric help acidity or indigestion?
That is a separate question from interactions. Our evidence page on curcumin for functional dyspepsia looks at the trials, including the one on this page.[1]
Related
Does curcumin help indigestion (functional dyspepsia)?
In a 132-person trial, curcumin eased indigestion more than placebo over four weeks. That does not make it equal to omeprazole.
ConditionAcidity, acid reflux and gastritis: what Ayurveda offers
Curcumin eased indigestion more than placebo in one small trial. We found no trial of Ayurveda for reflux disease or gastritis itself.
InteractionTurmeric and iron supplements
A man on high-dose turmeric stayed anaemic on iron until he stopped it. A one-dose curcumin trial found no drop in iron absorption.
InteractionTurmeric and painkillers like ibuprofen and diclofenac
No study has tested turmeric with NSAID painkillers. A regulator warns that turmeric supplements with these medicines may prolong bleeding.
Sources
- Kongkam P, Khongkha W, Lopimpisuth C, Chumsri C, Kosarussawadee P, Phutrakool P, Khamsai S, Sawanyawisuth K, Sura T, Phisalprapa P, Buamahakul T, Siwamogsatham S, Angsusing J, Poonniam P, Wanaratna K, Teerachaisakul M, Pongpirul K. Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial. BMJ Evid Based Med. 2023;28(6):399-406. PMID 37696679.
- Correction to: Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial. BMJ Evid Based Med. 2025;30(5):358. PMID 38866470.
Updated 4 November 2026
Taking turmeric with other medicines? A vaidya can check your full list.
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