Theoretical riskPending medical review

The short answer

Not known in people. We found no study of shilajit taken with a diuretic (water tablet). The only lab work linking them is a formulation experiment from Jamia Hamdard, New Delhi, in which fulvic acid extracted from shilajit was deliberately bonded to furosemide (Lasix) to study how the drug dissolves.

That shows the two can combine chemically in the lab. It does not show what happens when someone swallows shilajit alongside a water tablet, or which way furosemide levels would move. Shilajit products also vary in quality, and a 2025 analysis found thallium, a toxic metal, in some samples. If you take a diuretic, tell your prescribing doctor before you start shilajit.

Diuretics sold in India include Lasix (furosemide), Dytor (torsemide), Aquazide (hydrochlorothiazide) and Aldactone (spironolactone).

At a glance

What was seen	How it may work	Direction	Evidence
Fulvic acid from shilajit formed a complex with furosemide[1]	Chemical binding in a designed formulation	Could change how furosemide dissolves or is absorbed; direction unknown	In vitro
Thallium in raw shilajit and supplements[2]	Contamination, not an interaction	Exposure to a toxic metal	In vitro

No listing is not a clearance. A missing interaction here never means a combination is safe.

The evidence, study by study

Lab formulation study, New Delhi, 2008 In vitro

Pharmacy researchers at Jamia Hamdard combined furosemide with fulvic acid taken from shilajit, in one-to-one and one-to-two ratios, using grinding, freeze drying and other methods. Their tests confirmed that the furosemide sat inside a complex with the fulvic acid. This was formulation chemistry, not a test of the two taken together. It used purified fulvic acid, not shilajit resin, and gave nothing to animals or people.[1]

Lab analysis of shilajit products, Iran, Slovakia and Poland, 2025 In vitro

Thallium was found in most of 13 raw shilajit samples, from Iran, India, Nepal, Russia and Kyrgyzstan, and in supplements bought in Poland, Russia and Kyrgyzstan. The highest supplement level was 0.5 micrograms per gram, or up to 0.095 micrograms per tablet. No Indian brand was tested. This is a product-quality finding, separate from any effect on diuretics.[2]

What your doctor may watch for

Hydration, body salts (electrolytes) and kidney function, which are part of routine care on a diuretic. The furosemide label warns that too much of the drug can cause water and electrolyte depletion.[3]

What to tell your prescribing doctor

You can read this out, or show them this page:

“I am taking, or planning to take, shilajit (name of product, batch, dose) along with my water tablet. There is lab evidence that a compound from shilajit binds furosemide, but no study in people. Is there any reason to be careful, and should my salts or kidney function be checked?”

Withheld until review

Dose adjustments and any “no known interaction” clearance appear only after a vaidya on our medical board has reviewed this page. Why we hold these back

Questions people ask

What is fulvic acid?

It is one of the substances extracted from shilajit. The 2008 study used fulvic acid purified in the lab, which is not the same as the resin or capsules people buy.[1]

Are shilajit products tested for metals?

The 2025 analysis found thallium levels varied widely between samples, and its authors call for regular testing. They also cite earlier reports of arsenic, lead and mercury in shilajit. Show your doctor the pack, with its batch number.[2]

Interaction

Sources

Awaiting review by The Good Vaidya Medical Board. Prepared from the sources below and checked against each one.

Published 4 November 2026 · Last updated 4 November 2026

Taking shilajit with other medicines? A vaidya can check your full list.

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Shilajit and diuretics (water tablets)